Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay

Despite extensive research, the sequence features affecting microRNA-mediated regulation are not well understood, limiting our ability to predict gene expression levels in both native and synthetic sequences. Here we employed a massively parallel reporter assay to investigate the effect of over 14,0...

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Detalles Bibliográficos
Autores principales: Vainberg Slutskin, Ilya, Weingarten-Gabbay, Shira, Nir, Ronit, Weinberger, Adina, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802814/
https://www.ncbi.nlm.nih.gov/pubmed/29410437
http://dx.doi.org/10.1038/s41467-018-02980-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802814/
https://www.ncbi.nlm.nih.gov/pubmed/29410437
http://dx.doi.org/10.1038/s41467-018-02980-z

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