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Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay
Despite extensive research, the sequence features affecting microRNA-mediated regulation are not well understood, limiting our ability to predict gene expression levels in both native and synthetic sequences. Here we employed a massively parallel reporter assay to investigate the effect of over 14,0...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802814/ https://www.ncbi.nlm.nih.gov/pubmed/29410437 http://dx.doi.org/10.1038/s41467-018-02980-z |