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Ub-ProT reveals global length and composition of protein ubiquitylation in cells

Protein ubiquitylation regulates diverse cellular processes via distinct ubiquitin chains that differ by linkage type and length. However, a comprehensive method for measuring these properties has not been developed. Here we describe a method for assessing the length of substrate-attached polyubiqui...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Hikaru, Burana, Daocharad, Ohtake, Fumiaki, Arai, Naoko, Kaiho, Ai, Komada, Masayuki, Tanaka, Keiji, Saeki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802829/
https://www.ncbi.nlm.nih.gov/pubmed/29410401
http://dx.doi.org/10.1038/s41467-018-02869-x