Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking

Subcellular fine-tuning of the actomyosin cytoskeleton is a prerequisite for polarized cell migration. We identify LSP (lymphocyte-specific protein) 1 as a critical regulator of actomyosin contractility in primary macrophages. LSP1 regulates adhesion and migration, including the parameters cell area...

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Detalles Bibliográficos
Autores principales: Cervero, Pasquale, Wiesner, Christiane, Bouissou, Anais, Poincloux, Renaud, Linder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802837/
https://www.ncbi.nlm.nih.gov/pubmed/29410425
http://dx.doi.org/10.1038/s41467-018-02904-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802837/
https://www.ncbi.nlm.nih.gov/pubmed/29410425
http://dx.doi.org/10.1038/s41467-018-02904-x

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