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Polymerisation force of a rigid filament bundle: diffusive interaction leads to sublinear force-number scaling

Polymerising filaments generate force against an obstacle, as in, e.g., microtubule-kinetochore interactions in the eukaryotic cell. Earlier studies of this problem have not included explicit three-dimensional monomer diffusion, and consequently, missed out on two important aspects: (i) the barrier,...

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Detalles Bibliográficos
Autores principales: Valiyakath, Jemseena, Gopalakrishnan, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802839/
https://www.ncbi.nlm.nih.gov/pubmed/29410507
http://dx.doi.org/10.1038/s41598-018-20259-7