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Automated cell-type classification in intact tissues by single-cell molecular profiling

A major challenge in biology is identifying distinct cell classes and mapping their interactions in vivo. Tissue-dissociative technologies enable deep single cell molecular profiling but do not provide spatial information. We developed a proximity ligation in situ hybridization technology (PLISH) wi...

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Detalles Bibliográficos
Autores principales: Nagendran, Monica, Riordan, Daniel P, Harbury, Pehr B, Desai, Tushar J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802843/
https://www.ncbi.nlm.nih.gov/pubmed/29319504
http://dx.doi.org/10.7554/eLife.30510