The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study

A major constraint in the treatment of cancer is inadequate oxygenation of the tumor mass, which can reduce chemotherapeutic efficacy. We hypothesize that polymerized human hemoglobin (PolyhHb) can be transfused into the systemic circulation to increase solid tumor oxygenation, and improve chemother...

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Detalles Bibliográficos
Autores principales: Belcher, Donald A., Ju, Julia A., Baek, Jin Hyen, Yalamanoglu, Ayla, Buehler, Paul W., Gilkes, Daniele M., Palmer, Andre F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802857/
https://www.ncbi.nlm.nih.gov/pubmed/29414985
http://dx.doi.org/10.1371/journal.pone.0191275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802857/
https://www.ncbi.nlm.nih.gov/pubmed/29414985
http://dx.doi.org/10.1371/journal.pone.0191275

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