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SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML

Our previous studies demonstrated that INPP4B, a member of the PI3K/Akt signaling pathway, is overexpressed in a subset of AML patients and is associated with lower response to chemotherapy and shorter survival. INPP4B expression analysis in AML revealed a right skewed frequency distribution with 25...

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Detalles Bibliográficos
Autores principales: Dzneladze, Irakli, Woolley, John F., Rossell, Carla, Han, Youqi, Rashid, Ayesha, Jain, Michael, Reimand, Jüri, Minden, Mark D., Salmena, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802890/
https://www.ncbi.nlm.nih.gov/pubmed/29415082
http://dx.doi.org/10.1371/journal.pone.0191510