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MR-guided transcranial focused ultrasound safely enhances interstitial dispersion of large polymeric nanoparticles in the living brain

Generating spatially controlled, non-destructive changes in the interstitial spaces of the brain has a host of potential clinical applications, including enhancing the delivery of therapeutics, modulating biological features within the tissue microenvironment, altering fluid and pressure dynamics, a...

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Detalles Bibliográficos
Autores principales: Hersh, David S., Anastasiadis, Pavlos, Mohammadabadi, Ali, Nguyen, Ben A., Guo, Sijia, Winkles, Jeffrey A., Kim, Anthony J., Gullapalli, Rao, Keller, Asaf, Frenkel, Victor, Woodworth, Graeme F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802894/
https://www.ncbi.nlm.nih.gov/pubmed/29415084
http://dx.doi.org/10.1371/journal.pone.0192240