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MR-guided transcranial focused ultrasound safely enhances interstitial dispersion of large polymeric nanoparticles in the living brain
Generating spatially controlled, non-destructive changes in the interstitial spaces of the brain has a host of potential clinical applications, including enhancing the delivery of therapeutics, modulating biological features within the tissue microenvironment, altering fluid and pressure dynamics, a...
Autores principales: | Hersh, David S., Anastasiadis, Pavlos, Mohammadabadi, Ali, Nguyen, Ben A., Guo, Sijia, Winkles, Jeffrey A., Kim, Anthony J., Gullapalli, Rao, Keller, Asaf, Frenkel, Victor, Woodworth, Graeme F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802894/ https://www.ncbi.nlm.nih.gov/pubmed/29415084 http://dx.doi.org/10.1371/journal.pone.0192240 |
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