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BACHD rats expressing full-length mutant huntingtin exhibit differences in social behavior compared to wild-type littermates
BACKGROUND: Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without any cure to slow down or stop the progress of the disease. The BACHD rat model for HD carrying the human full-length mutant huntin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802907/ https://www.ncbi.nlm.nih.gov/pubmed/29415038 http://dx.doi.org/10.1371/journal.pone.0192289 |