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BACHD rats expressing full-length mutant huntingtin exhibit differences in social behavior compared to wild-type littermates

BACKGROUND: Huntington disease (HD) is a devastating inherited neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms without any cure to slow down or stop the progress of the disease. The BACHD rat model for HD carrying the human full-length mutant huntin...

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Detalles Bibliográficos
Autores principales:	Manfré, Giuseppe, Novati, Arianna, Faccini, Ilaria, Rossetti, Andrea C., Bosch, Kari, Molteni, Raffaella, Riva, Marco A., Van der Harst, Johanneke E., Nguyen, Huu Phuc, Homberg, Judith R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802907/ https://www.ncbi.nlm.nih.gov/pubmed/29415038 http://dx.doi.org/10.1371/journal.pone.0192289

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