A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy

The Double homeobox 4 (DUX4) gene is an important regulator of early human development and its aberrant expression is causal for facioscapulohumeral muscular dystrophy (FSHD). The DUX4-full length (DUX4-fl) mRNA splice isoform encodes a transcriptional activator; however, DUX4 and its unique DNA bin...

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Detalles Bibliográficos
Autores principales: Jones, Takako, Jones, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802938/
https://www.ncbi.nlm.nih.gov/pubmed/29415061
http://dx.doi.org/10.1371/journal.pone.0192657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802938/
https://www.ncbi.nlm.nih.gov/pubmed/29415061
http://dx.doi.org/10.1371/journal.pone.0192657

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