Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels

The rates of opioid prescription and use have continued to increase over the last few decades resulting in a greater number of opioid tolerant patients. Treatment of acute pain from surgery and injury is a clinical challenge for these patients. Several pain management strategies including prescribin...

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Detalles Bibliográficos
Autores principales: Schaefer, Charles P., Arkwright, Nathan B., Jacobs, Leigh M., Jarvis, Chelsea K., Hunn, Kristen C., Largent-Milnes, Tally M., Tome, Margaret E., Davis, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802945/
https://www.ncbi.nlm.nih.gov/pubmed/29414996
http://dx.doi.org/10.1371/journal.pone.0192340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802945/
https://www.ncbi.nlm.nih.gov/pubmed/29414996
http://dx.doi.org/10.1371/journal.pone.0192340

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