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Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels
The rates of opioid prescription and use have continued to increase over the last few decades resulting in a greater number of opioid tolerant patients. Treatment of acute pain from surgery and injury is a clinical challenge for these patients. Several pain management strategies including prescribin...
Autores principales: | Schaefer, Charles P., Arkwright, Nathan B., Jacobs, Leigh M., Jarvis, Chelsea K., Hunn, Kristen C., Largent-Milnes, Tally M., Tome, Margaret E., Davis, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802945/ https://www.ncbi.nlm.nih.gov/pubmed/29414996 http://dx.doi.org/10.1371/journal.pone.0192340 |
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