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Intrathecal Noggin administration in rats temporally ameliorates mechanical allodynia induced by a chronic constriction injury

Chronic intractable neuropathic pain after central or peripheral nervous system injury remains refractory to therapeutic intervention. Using microarray and RT-qPCR methods, we found that Noggin mRNA is downregulated in the lumbar enlargement 2 weeks after chronic constriction injury (CCI) in rats. E...

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Detalles Bibliográficos
Autores principales: Hashimoto, Masayuki, Koda, Masao, Furuya, Takeo, Murata, Atsushi, Yamazaki, Masashi, Takahashi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803104/
https://www.ncbi.nlm.nih.gov/pubmed/29430541
http://dx.doi.org/10.1016/j.ensci.2016.03.001