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Intrathecal Noggin administration in rats temporally ameliorates mechanical allodynia induced by a chronic constriction injury
Chronic intractable neuropathic pain after central or peripheral nervous system injury remains refractory to therapeutic intervention. Using microarray and RT-qPCR methods, we found that Noggin mRNA is downregulated in the lumbar enlargement 2 weeks after chronic constriction injury (CCI) in rats. E...
Autores principales: | Hashimoto, Masayuki, Koda, Masao, Furuya, Takeo, Murata, Atsushi, Yamazaki, Masashi, Takahashi, Kazuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803104/ https://www.ncbi.nlm.nih.gov/pubmed/29430541 http://dx.doi.org/10.1016/j.ensci.2016.03.001 |
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