Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells

Platforms for targeted drug-delivery must simultaneously exhibit serum stability, efficient directed cell internalization, and triggered drug release. Here, using lipid-mediated self-assembly of aptamers, we combine multiple structural motifs into a single nanoconstruct that targets hepatocyte growt...

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Detalles Bibliográficos
Autores principales: Prusty, Deepak K., Adam, Volker, Zadegan, Reza M., Irsen, Stephan, Famulok, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803212/
https://www.ncbi.nlm.nih.gov/pubmed/29416033
http://dx.doi.org/10.1038/s41467-018-02929-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803212/
https://www.ncbi.nlm.nih.gov/pubmed/29416033
http://dx.doi.org/10.1038/s41467-018-02929-2

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