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Structural basis for amino acid transport by the CAT family of SLC7 transporters

Amino acids play essential roles in cell biology as regulators of metabolic pathways. Arginine in particular is a major signalling molecule inside the cell, being a precursor for both l-ornithine and nitric oxide (NO) synthesis and a key regulator of the mTORC1 pathway. In mammals, cellular arginine...

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Detalles Bibliográficos
Autores principales: Jungnickel, Katharina E. J., Parker, Joanne L., Newstead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803215/
https://www.ncbi.nlm.nih.gov/pubmed/29416041
http://dx.doi.org/10.1038/s41467-018-03066-6