Cargando…

Structural basis for amino acid transport by the CAT family of SLC7 transporters

Amino acids play essential roles in cell biology as regulators of metabolic pathways. Arginine in particular is a major signalling molecule inside the cell, being a precursor for both l-ornithine and nitric oxide (NO) synthesis and a key regulator of the mTORC1 pathway. In mammals, cellular arginine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jungnickel, Katharina E. J., Parker, Joanne L., Newstead, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803215/ https://www.ncbi.nlm.nih.gov/pubmed/29416041 http://dx.doi.org/10.1038/s41467-018-03066-6

Ejemplares similares

Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters
por: Minhas, Gurdeep S., et al.
Publicado: (2019)

Structural basis of nucleotide sugar transport across the Golgi membrane
por: Parker, Joanne L, et al.
Publicado: (2017)

Structural basis for recognition and transport of folic acid in mammalian cells
por: Newstead, Simon
Publicado: (2022)

Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters
por: Lyons, Joseph A, et al.
Publicado: (2014)

Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters
por: Minhas, Gurdeep S., et al.
Publicado: (2020)

Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1
por: Parker, Joanne L., et al.
Publicado: (2014)

Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer
por: Parker, Joanne L., et al.
Publicado: (2019)

Structural basis for proton coupled cystine transport by cystinosin
por: Löbel, Mark, et al.
Publicado: (2022)

Proton Control of Transitions in an Amino Acid Transporter
por: Wu, Zhiyi, et al.
Publicado: (2019)

Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter
por: Parker, Joanne L, et al.
Publicado: (2014)

Molecular insights into proton coupled peptide transport in the PTR family of oligopeptide transporters()
por: Newstead, Simon
Publicado: (2015)

Structural basis for functional interactions in dimers of SLC26 transporters
por: Chang, Yung-Ning, et al.
Publicado: (2019)

The neutral amino acid transporter SLC7A10 in adipose tissue, obesity and insulin resistance
por: Jersin, Regine Åsen, et al.
Publicado: (2022)

Structural basis of malodour precursor transport in the human axilla
por: Minhas, Gurdeep S, et al.
Publicado: (2018)

Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
por: Ehrnstorfer, Ines A., et al.
Publicado: (2017)

Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals
por: Parker, Joanne L., et al.
Publicado: (2021)

Ubiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter
por: Barthelemy, Céline, et al.
Publicado: (2019)

Mechanistic basis of L-lactate transport in the SLC16 solute carrier family
por: Bosshart, Patrick D., et al.
Publicado: (2019)

Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2)
por: Edwards, Noel, et al.
Publicado: (2011)

Expression profile of the amino acid transporters SLC7A5, SLC7A7, SLC7A8 and the enzyme TDO2 in basal cell carcinoma
por: Tina, E., et al.
Publicado: (2018)

The zebrafish cationic amino acid transporter/glycoprotein-associated family: sequence and spatiotemporal distribution during development of the transport system b(0,+) (slc3a1/slc7a9)
por: Ellingsen, Ståle, et al.
Publicado: (2021)

The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)
por: Cormerais, Yann, et al.
Publicado: (2018)

Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters
por: Alleva, Claudia, et al.
Publicado: (2021)

Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters
por: Gorbunov, Dmitry, et al.
Publicado: (2014)

Toward a Systematic Structural and Functional Annotation of Solute Carriers Transporters—Example of the SLC6 and SLC7 Families
por: Colas, Claire
Publicado: (2020)

Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark
por: Scalise, Mariafrancesca, et al.
Publicado: (2021)

Nucleotide Sugar Transporter SLC35 Family Structure and Function
por: Hadley, Barbara, et al.
Publicado: (2019)

SLC Solute Carrier Transporters and Neurodegenerative Disorders: Drawing Attention to Cationic Amino Acid Transporters 1 and 2
por: Bernstein, Hans-Gert, et al.
Publicado: (2020)

The Genetic Variability of Members of the SLC38 Family of Amino Acid Transporters (SLC38A3, SLC38A7 and SLC38A9) Affects Susceptibility to Type 2 Diabetes and Vascular Complications
por: Crocco, Paolina, et al.
Publicado: (2022)

The Evaluation of l‐Tryptophan Derivatives as Inhibitors of the l‐Type Amino Acid Transporter LAT1 (SLC7A5)
por: Graff, Julien, et al.
Publicado: (2022)

Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line
por: Takahashi, Yu, et al.
Publicado: (2018)

Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
por: Gorecki, Matthias, et al.
Publicado: (2020)

The D‐amino acid transport by the invertebrate SLC6 transporters KAAT1 and CAATCH1 from Manduca sexta
por: Vollero, Alessandra, et al.
Publicado: (2016)

The amino acid transporter Slc7a5 regulates the mTOR pathway and is required for granule cell development
por: Sokolov, Aidan M, et al.
Publicado: (2020)

Exploiting the metabolic dependencies of the broad amino acid transporter SLC6A14
por: Dejure, Francesca R., et al.
Publicado: (2020)

Proton movement and coupling in the POT family of peptide transporters
por: Parker, Joanne L., et al.
Publicado: (2017)

Structure and Function of SLC4 Family [Formula: see text] Transporters
por: Liu, Ying, et al.
Publicado: (2015)

Structure, function and regulation of mammalian glucose transporters of the SLC2 family
por: Holman, Geoffrey D.
Publicado: (2020)

Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
por: Koppula, Pranavi, et al.
Publicado: (2018)

Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia
por: Deng, Xiangdong, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_dg53ksc7qq0b4t8c735eqi2uv2