EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells

Hepatic fibrosis is the result of an excessive wound-healing response subsequent to chronic liver injury. A feature of liver fibrogenesis is the secretion and deposition of extracellular matrix proteins by activated hepatic stellate cells (HSCs). Here we report that upregulation of EphB2 is a promin...

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Detalles Bibliográficos
Autores principales: Mimche, Patrice N., Lee, Choon M., Mimche, Sylvie M., Thapa, Manoj, Grakoui, Arash, Henkemeyer, Mark, Lamb, Tracey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803231/
https://www.ncbi.nlm.nih.gov/pubmed/29416088
http://dx.doi.org/10.1038/s41598-018-20926-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803231/
https://www.ncbi.nlm.nih.gov/pubmed/29416088
http://dx.doi.org/10.1038/s41598-018-20926-9

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