IRE1α siRNA relieves endoplasmic reticulum stress-induced apoptosis and alleviates diabetic peripheral neuropathy in vivo and in vitro

Diabetic peripheral neuropathy (DPN) is mainly characterized by demyelination resulted from the apoptosis of the Schwann cell (SCs). Although the exact mechanisms underlying DPN remain unclear, endoplasmic reticulum (ER) stress is strongly implicated in the apoptosis. Under ER stress, activated inos...

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Detalles Bibliográficos
Autores principales: Yao, Weijie, Yang, Xinwei, Zhu, Jiayue, Gao, Biane, Shi, Haotian, Xu, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803253/
https://www.ncbi.nlm.nih.gov/pubmed/29416111
http://dx.doi.org/10.1038/s41598-018-20950-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803253/
https://www.ncbi.nlm.nih.gov/pubmed/29416111
http://dx.doi.org/10.1038/s41598-018-20950-9

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