Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries

The metazoan genome is compartmentalized in areas of highly interacting chromatin known as topologically associating domains (TADs). TADs are demarcated by boundaries mostly conserved across cell types and even across species. However, a genome-wide characterization of TAD boundary strength in mamma...

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Detalles Bibliográficos
Autores principales: Gong, Yixiao, Lazaris, Charalampos, Sakellaropoulos, Theodore, Lozano, Aurelie, Kambadur, Prabhanjan, Ntziachristos, Panagiotis, Aifantis, Iannis, Tsirigos, Aristotelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803259/
https://www.ncbi.nlm.nih.gov/pubmed/29416042
http://dx.doi.org/10.1038/s41467-018-03017-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803259/
https://www.ncbi.nlm.nih.gov/pubmed/29416042
http://dx.doi.org/10.1038/s41467-018-03017-1

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