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Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
The metazoan genome is compartmentalized in areas of highly interacting chromatin known as topologically associating domains (TADs). TADs are demarcated by boundaries mostly conserved across cell types and even across species. However, a genome-wide characterization of TAD boundary strength in mamma...
Autores principales: | Gong, Yixiao, Lazaris, Charalampos, Sakellaropoulos, Theodore, Lozano, Aurelie, Kambadur, Prabhanjan, Ntziachristos, Panagiotis, Aifantis, Iannis, Tsirigos, Aristotelis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803259/ https://www.ncbi.nlm.nih.gov/pubmed/29416042 http://dx.doi.org/10.1038/s41467-018-03017-1 |
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