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Akt regulates neurite growth by phosphorylation-dependent inhibition of radixin proteasomal degradation

Neurite growth is controlled by a complex molecular signaling network that regulates filamentous actin (F-actin) dynamics at the growth cone. The evolutionarily conserved ezrin, radixin, and moesin family of proteins tether F-actin to the cell membrane when phosphorylated at a conserved threonine re...

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Detalles Bibliográficos
Autores principales: Jin, Eun-Ju, Ko, Hyo Rim, Hwang, Inwoo, Kim, Byeong-Seong, Choi, Jeong-Yun, Park, Kye Won, Cho, Sung-Woo, Ahn, Jee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803261/
https://www.ncbi.nlm.nih.gov/pubmed/29416050
http://dx.doi.org/10.1038/s41598-018-20755-w