Static compression down-regulates N-cadherin expression and facilitates loss of cell phenotype of nucleus pulposus cells in a disc perfusion culture

Mechanical compression often induces degenerative changes of disc nucleus pulposus (NP) tissue. It has been indicated that N-cadherin (N-CDH)-mediated signaling helps to preserve the NP cell phenotype. However, N-CDH expression and the resulting NP-specific phenotype alteration under the static comp...

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Detalles Bibliográficos
Autores principales: Zhou, Haibo, Shi, Jianmin, Zhang, Chao, Li, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803491/
https://www.ncbi.nlm.nih.gov/pubmed/29273678
http://dx.doi.org/10.1042/BSR20171551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803491/
https://www.ncbi.nlm.nih.gov/pubmed/29273678
http://dx.doi.org/10.1042/BSR20171551

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