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Molecular basis for potentiation of Cx36 gap junction channel conductance by n-alcohols and general anesthetics

In our recent study, we have demonstrated that short carbon chain n-alcohols (up to octanol) stimulated while long carbon chain n-alcohols inhibited the conductance of connexin (Cx) 36 (Cx36) gap junction (GJ) channels. In contrast, GJ channels composed of other types of Cxs all were inhibited by n-...

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Detalles Bibliográficos
Autores principales: Raškevičius, Vytautas, Jotautis, Vaidas, Rimkutė, Lina, Marandykina, Alina, Kazokaitė, Mintautė, Kairys, Visvaldas, Skeberdis, Vytenis Arvydas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803492/
https://www.ncbi.nlm.nih.gov/pubmed/29298877
http://dx.doi.org/10.1042/BSR20171323