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iNKT cells prevent obesity-induced hepatic steatosis in mice in a C-C chemokine receptor 7-dependent manner

Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are characterized by an increase in hepatic triglyceride content with infiltration of immune cells, which can cause steatohepatitis and hepatic insulin resistance. C-C chemokine receptor 7 (CCR7) is primarily expressed in immune cel...

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Detalles Bibliográficos
Autores principales: Kim, H M, Lee, B R, Lee, E S, Kwon, M H, Huh, J H, Kwon, B-E, Park, E-K, Chang, S-Y, Kweon, M-N, Kim, P-H, Ko, H-J, Chung, C H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803573/
https://www.ncbi.nlm.nih.gov/pubmed/28811651
http://dx.doi.org/10.1038/ijo.2017.200