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Differentially expressed alternatively spliced genes in skeletal muscle from cancer patients with cachexia

BACKGROUND: Alternative splicing (AS) is a post‐transcriptional gene regulatory mechanism that contributes to proteome diversity. Aberrant splicing mechanisms contribute to various cancers and muscle‐related conditions such as Duchenne muscular dystrophy. However, dysregulation of AS in cancer cache...

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Detalles Bibliográficos
Autores principales: Narasimhan, Ashok, Greiner, Russell, Bathe, Oliver F., Baracos, Vickie, Damaraju, Sambasivarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803615/
https://www.ncbi.nlm.nih.gov/pubmed/28984045
http://dx.doi.org/10.1002/jcsm.12235