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A muscle‐specific MuRF1‐E2 network requires stabilization of MuRF1‐E2 complexes by telethonin, a newly identified substrate

BACKGROUND: Muscle wasting is observed in the course of many diseases and also during physiological conditions (disuse, ageing). Skeletal muscle mass is largely controlled by the ubiquitin‐proteasome system and thus by the ubiquitinating enzymes (E2s and E3s) that target substrates for subsequent de...

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Detalles Bibliográficos
Autores principales: Polge, Cécile, Cabantous, Stéphanie, Deval, Christiane, Claustre, Agnès, Hauvette, Antoine, Bouchenot, Catherine, Aniort, Julien, Béchet, Daniel, Combaret, Lydie, Attaix, Didier, Taillandier, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803617/
https://www.ncbi.nlm.nih.gov/pubmed/29271608
http://dx.doi.org/10.1002/jcsm.12249