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Fosfomycin as a potential therapy for the treatment of systemic infections: a population pharmacokinetic model to simulate multiple dosing regimens

Fosfomycin has emerged as a potential therapy for multidrug‐resistant bacterial infections. In most European countries, the oral formulation is only approved as a 3 g single dose for treatment of uncomplicated cystitis. However, for the treatment of complicated systemic infections, this dose regimen...

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Detalles Bibliográficos
Autores principales: Ortiz Zacarías, Natalia V., Dijkmans, Anneke C., Burggraaf, Jacobus, Mouton, Johan W., Wilms, Erik B., van Nieuwkoop, Cees, Touw, Daan J., Kamerling, Ingrid M. C., Stevens, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803932/
https://www.ncbi.nlm.nih.gov/pubmed/29417760
http://dx.doi.org/10.1002/prp2.378