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Xanthine oxidase inhibitors for prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials

BACKGROUND: Xanthine oxidase inhibitors (XOI), classified as purine-like (allopurinol and oxypurinol) and non-purine (febuxostat and topiroxostat) XOI, present antioxidant properties by reducing the production of reactive oxygen species derived from purine metabolism. Oxidative stress is an importan...

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Detalles Bibliográficos
Autores principales: Bredemeier, Markus, Lopes, Lediane Moreira, Eisenreich, Matheus Augusto, Hickmann, Sheila, Bongiorno, Guilherme Kopik, d’Avila, Rui, Morsch, André Luis Bittencourt, da Silva Stein, Fernando, Campos, Guilherme Gomes Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804046/
https://www.ncbi.nlm.nih.gov/pubmed/29415653
http://dx.doi.org/10.1186/s12872-018-0757-9