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Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates
BACKGROUND: Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is one of leading blood stage malaria vaccine candidates. However, genetic variation and antigenic diversity identified in global PfAMA-1 are major hurdles in the development of an effective vaccine based on this antigen. In this...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804060/ https://www.ncbi.nlm.nih.gov/pubmed/29415731 http://dx.doi.org/10.1186/s12936-018-2215-7 |