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Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates

BACKGROUND: Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is one of leading blood stage malaria vaccine candidates. However, genetic variation and antigenic diversity identified in global PfAMA-1 are major hurdles in the development of an effective vaccine based on this antigen. In this...

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Detalles Bibliográficos
Autores principales: Kang, Jung-Mi, Lee, Jinyoung, Moe, Mya, Jun, Hojong, Lê, Hương Giang, Kim, Tae Im, Thái, Thị Lam, Sohn, Woon-Mok, Myint, Moe Kyaw, Lin, Khin, Shin, Ho-Joon, Kim, Tong-Soo, Na, Byoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804060/
https://www.ncbi.nlm.nih.gov/pubmed/29415731
http://dx.doi.org/10.1186/s12936-018-2215-7