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Swinepox virus vector-based vaccines: attenuation and biosafety assessments following subcutaneous prick inoculation
Swinepox virus (SPV) has several advantages as a potential clinical vector for a live vector vaccine. In this study, to obtain a safer and more efficient SPV vector, three SPV mutants, Δ003, Δ010, and ΔTK were successfully constructed. A virus replication experiment showed that these SPV mutants had...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804073/ https://www.ncbi.nlm.nih.gov/pubmed/29415767 http://dx.doi.org/10.1186/s13567-018-0510-5 |