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Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery

Accurate typing of human leukocyte antigen (HLA) is important because HLA genes play important roles in immune responses and disease genesis. Previously available computational methods are database-matching approaches and their outputs are inherently limited by the completeness of already known type...

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Detalles Bibliográficos
Autores principales: Lee, Heewook, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804087/
https://www.ncbi.nlm.nih.gov/pubmed/29415772
http://dx.doi.org/10.1186/s13059-018-1388-2