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Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery
Accurate typing of human leukocyte antigen (HLA) is important because HLA genes play important roles in immune responses and disease genesis. Previously available computational methods are database-matching approaches and their outputs are inherently limited by the completeness of already known type...
Autores principales: | Lee, Heewook, Kingsford, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804087/ https://www.ncbi.nlm.nih.gov/pubmed/29415772 http://dx.doi.org/10.1186/s13059-018-1388-2 |
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