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Complex versus simple models: ion-channel cardiac toxicity prediction

There is growing interest in applying detailed mathematical models of the heart for ion-channel related cardiac toxicity prediction. However, a debate as to whether such complex models are required exists. Here an assessment in the predictive performance between two established large-scale biophysic...

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Detalles Bibliográficos
Autor principal: Mistry, Hitesh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804316/
https://www.ncbi.nlm.nih.gov/pubmed/29423349
http://dx.doi.org/10.7717/peerj.4352