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Idh2 Deficiency Exacerbates Acrolein-Induced Lung Injury through Mitochondrial Redox Environment Deterioration

Acrolein is known to be involved in acute lung injury and other pulmonary diseases. A number of studies have suggested that acrolein-induced toxic effects are associated with depletion of antioxidants, such as reduced glutathione and protein thiols, and production of reactive oxygen species. Mitocho...

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Detalles Bibliográficos
Autores principales: Park, Jung Hyun, Ku, Hyeong Jun, Lee, Jin Hyup, Park, Jeen-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804324/
https://www.ncbi.nlm.nih.gov/pubmed/29456784
http://dx.doi.org/10.1155/2017/1595103