Pluripotent Stem Cell-Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety

Despite the improvements in drug screening, high levels of drug attrition persist. Although high-throughput screening platforms permit the testing of compound libraries, poor compound efficacy or unexpected organ toxicity are major causes of attrition. Part of the reason for drug failure resides in...

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Detalles Bibliográficos
Autores principales: Meseguer-Ripolles, Jose, Khetani, Salman R., Blanco, Javier G., Iredale, Mairi, Hay, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804345/
https://www.ncbi.nlm.nih.gov/pubmed/29270863
http://dx.doi.org/10.1208/s12248-017-0171-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804345/
https://www.ncbi.nlm.nih.gov/pubmed/29270863
http://dx.doi.org/10.1208/s12248-017-0171-8

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