Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway

Acquired resistance to cisplatin is the most common reason for the failure of cisplatin chemotherapy. Hederagenin, triterpenoids extracted from ivy leaves, exhibits antitumor activity in various types of cancer. However, the therapeutic potential of hederagenin in head and neck cancer (HNC) has rema...

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Detalles Bibliográficos
Autores principales: Kim, Eun Hye, Baek, Seungho, Shin, Daiha, Lee, Jaewang, Roh, Jong-Lyel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804377/
https://www.ncbi.nlm.nih.gov/pubmed/29456786
http://dx.doi.org/10.1155/2017/5498908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804377/
https://www.ncbi.nlm.nih.gov/pubmed/29456786
http://dx.doi.org/10.1155/2017/5498908

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