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Comparison of (68)Ga-DOTA-Siglec-9 and (18)F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry

Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a ligand of inflammation-inducible vascular adhesion protein-1 (VAP-1). We compared (68)Ga-DOTA- and (18)F-fluorodeoxyribose- (FDR-) labeled Siglec-9 motif peptides for PET imaging of inflammation. Methods. Firstly, we examined (68)Ga-DO...

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Detalles Bibliográficos
Autores principales: Virtanen, Helena, Silvola, Johanna M. U., Autio, Anu, Li, Xiang-Guo, Liljenbäck, Heidi, Hellberg, Sanna, Siitonen, Riikka, Ståhle, Mia, Käkelä, Meeri, Airaksinen, Anu J., Helariutta, Kerttuli, Tolvanen, Tuula, Veres, Tibor Z., Saraste, Antti, Knuuti, Juhani, Jalkanen, Sirpa, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804415/
https://www.ncbi.nlm.nih.gov/pubmed/29463960
http://dx.doi.org/10.1155/2017/7645070