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Prenatal lead exposure is associated with decreased cord blood DNA methylation of the glycoprotein VI gene involved in platelet activation and thrombus formation

Early-life lead exposure impairs neurodevelopment and later exposure affects the cardiovascular system. Lead has been associated with reduced global 5-methylcytosine DNA methylation, suggesting that lead toxicity acts through epigenetic mechanisms. The objective of this study is to clarify how early...

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Detalles Bibliográficos
Autores principales: Engström, Karin, Rydbeck, Filip, Kippler, Maria, Wojdacz, Tomasz K., Arifeen, Shams, Vahter, Marie, Broberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804686/
https://www.ncbi.nlm.nih.gov/pubmed/29492281
http://dx.doi.org/10.1093/eep/dvv007