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A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer

Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function. The resulting modifications induce inflammation by binding to scavenger receptors. An in...

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Detalles Bibliográficos
Autores principales: Wendel, Ulrika, Persson, Nina, Risinger, Christian, Bengtsson, Eva, Nodin, Björn, Danielsson, Lena, Welinder, Charlotte, Nordin Fredrikson, Gunilla, Jansson, Bo, Blixt, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805250/
https://www.ncbi.nlm.nih.gov/pubmed/29420566
http://dx.doi.org/10.1371/journal.pone.0191872