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The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity

Dipeptidyl peptidase III (DPP III) isolated from the thermophilic bacteria Caldithrix abyssi (Ca) is a two-domain zinc exopeptidase, a member of the M49 family. Like other DPPs III, it cleaves dipeptides from the N-terminus of its substrates but differently from human, yeast and Bacteroides thetaiot...

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Detalles Bibliográficos
Autores principales: Sabljić, Igor, Tomin, Marko, Matovina, Mihaela, Sučec, Iva, Tomašić Paić, Ana, Tomić, Antonija, Abramić, Marija, Tomić, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805324/
https://www.ncbi.nlm.nih.gov/pubmed/29420664
http://dx.doi.org/10.1371/journal.pone.0192488