Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication

The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of viral replication, including transcription, splicing, nuclear export, translation, packaging and reverse transcription. Nonetheless, chemical probing and other approaches suggest that the HIV-1 genome m...

Descripción completa

Detalles Bibliográficos
Autores principales: Takata, Matthew A., Soll, Steven J., Emery, Ann, Blanco-Melo, Daniel, Swanstrom, Ronald, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805364/
https://www.ncbi.nlm.nih.gov/pubmed/29377940
http://dx.doi.org/10.1371/journal.ppat.1006824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805364/
https://www.ncbi.nlm.nih.gov/pubmed/29377940
http://dx.doi.org/10.1371/journal.ppat.1006824

Ejemplares similares