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Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of viral replication, including transcription, splicing, nuclear export, translation, packaging and reverse transcription. Nonetheless, chemical probing and other approaches suggest that the HIV-1 genome m...
Autores principales: | Takata, Matthew A., Soll, Steven J., Emery, Ann, Blanco-Melo, Daniel, Swanstrom, Ronald, Bieniasz, Paul D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805364/ https://www.ncbi.nlm.nih.gov/pubmed/29377940 http://dx.doi.org/10.1371/journal.ppat.1006824 |
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