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The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization

Circadian clocks are molecular timekeeping mechanisms that allow organisms to anticipate daily changes in their environment. The fundamental cellular basis of these clocks is delayed negative feedback gene regulation with PERIOD and CRYPTOCHROME containing protein complexes as main inhibitory elemen...

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Detalles Bibliográficos
Autores principales: Korge, Sandra, Maier, Bert, Brüning, Franziska, Ehrhardt, Lea, Korte, Thomas, Mann, Matthias, Herrmann, Andreas, Robles, Maria S., Kramer, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805371/
https://www.ncbi.nlm.nih.gov/pubmed/29377895
http://dx.doi.org/10.1371/journal.pgen.1007189