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The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization
Circadian clocks are molecular timekeeping mechanisms that allow organisms to anticipate daily changes in their environment. The fundamental cellular basis of these clocks is delayed negative feedback gene regulation with PERIOD and CRYPTOCHROME containing protein complexes as main inhibitory elemen...
Autores principales: | Korge, Sandra, Maier, Bert, Brüning, Franziska, Ehrhardt, Lea, Korte, Thomas, Mann, Matthias, Herrmann, Andreas, Robles, Maria S., Kramer, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805371/ https://www.ncbi.nlm.nih.gov/pubmed/29377895 http://dx.doi.org/10.1371/journal.pgen.1007189 |
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