MELK expression correlates with tumor mitotic activity but is not required for cancer growth

The Maternal Embryonic Leucine Zipper Kinase (MELK) has been identified as a promising therapeutic target in multiple cancer types. MELK over-expression is associated with aggressive disease, and MELK has been implicated in numerous cancer-related processes, including chemotherapy resistance, stem c...

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Detalles Bibliográficos
Autores principales: Giuliano, Christopher J, Lin, Ann, Smith, Joan C, Palladino, Ann C, Sheltzer, Jason M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805410/
https://www.ncbi.nlm.nih.gov/pubmed/29417930
http://dx.doi.org/10.7554/eLife.32838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805410/
https://www.ncbi.nlm.nih.gov/pubmed/29417930
http://dx.doi.org/10.7554/eLife.32838

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