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Inferring modes of evolution from colorectal cancer with residual polyp of origin

Besides the classical evolutionary model of colorectal cancer (CRC) defined by the stepwise accumulation of mutations in which normal epithelium transforms through an intermediary polyp stage to cancer, a few studies have proposed alternative modes of evolution (MOE): early eruptive subclonal expans...

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Detalles Bibliográficos
Autores principales: Kim, Minsoo, Druliner, Brooke R., Vasmatzis, Nikolaos, Bae, Taejeong, Chia, Nicholas, Abyzov, Alexej, Boardman, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805514/
https://www.ncbi.nlm.nih.gov/pubmed/29467928
http://dx.doi.org/10.18632/oncotarget.23687